Internship, Research Associate Bioinformatics & Data Sciences

Monte Rosa Therapeutics is seeking an Intern in Bioinformatics Data Sciences to contribute to the elimination of disease-causing proteins through targeted protein degradation—a groundbreaking approach designed to address proteins previously considered undruggable. Successful candidates will gain direct experience within an early-stage drug discovery environment and have the opportunity to focus on areas that align with their interests. You will work closely with industry leaders who will mentor you throughout your project, expose you to additional drug discovery initiatives, and guide you in solving complex biological challenges. Join a diverse, collaborative, and dynamic team that values innovation, teamwork, and a people-centric culture!

If you are interested in contributing to projects in the following areas, you will gain valuable hands-on experience and educational exposure in a fast-paced drug discovery environment

Bioinformatics & Data Analysis

• Design, implement, and optimize end-to-end pipelines for:
  • Bulk RNA-seq, single-cell RNA-seq.
  • Microarray and legacy transcriptomic platforms.
• Perform high-quality differential expression analysis, clustering, pathway enrichment, gene set annotation, and downstream biological interpretation.
• Curate and integrate data from public repositories (GEO, Single Cell Portal, ArrayExpress, etc.).
• Apply and benchmark multiple analytical frameworks (Seurat, Scanpy, DESeq2, edgeR, limma, etc).

Production & Engineering Collaboration

• Work closely with software engineers /IT to productionize bioinformatics pipelines, exposing core functionalities through APIs, dashboards, or internal platforms.
• Optimize workflows for scalability, reproducibility, and automation (Docker/Snakemake/Nextflow/Prefect/Airflow).
• Define data standards, schema, and metadata conventions for large-scale bioinformatics data ingestion.