Rise Internship - Targeting Cns Meninges

Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft. Werde Teil von Roche, wo jede Stimme zählt.

Die Position

The RiSE program (Roche Internships for Scientific Exchange) is a highly
competitive student research program at Roche. It offers the most talented graduate and medical degree students the opportunity to be fully integrated into our interdisciplinary and international industry R environment. As a RiSE student you will enhance your competencies, gain valuable work experience with us, and eventually become part of a world-wide network of RiSE Alumni.

The Neuroscience and Rare Diseases Discovery and Translational Area (NRD DTA) is developing medicines for a range of serious neurological diseases, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autism, spinal muscular atrophy, and Huntington’s disease.

As a RiSE student in the NRD DTA you will join the Neurovascular Distribution Lab and work on a joint project between the Neuroimmunology and Neurotechnologies sections at the Roche Innovation Center Basel, Switzerland. We are a
multidisciplinary team with expertise in neuroimmunology, neurovascular biology, blood-brain barrier function, disease biology and in vivo models of the central nervous system.

The Opportunity

• Performing exploratory lab work to investigate the targeting of the CNS meninges using various modalities in vivo
• Visualizing the cranio-meningeal compartment and exploring suitable delivery methods
• Performing animal work (LTK1 or similar required)
• Optimizing dissection and staining conditions for dura and leptomeninges
• Applying state of the art imaging techniques including confocal microscopy
• Using state-of-the-art tissue clearing and lightsheet microscopy to analyze the intact cranio-meningeal compartment
• Summarizing your work for internal and external meetings and draft a publication
• You will be hosted and mentored by a Roche scientist who will guide you through your research and provide you with the needed work infrastructure and collaborative network

Who You Are

• You graduated with a Master's degree less than a year ago OR you are enrolled in a PhD or medical degree program at a university.
• You are looking to expand your experience with an industry internship.
• You hold a valid LTK1/FELASA B animal licence.
• You are proficient in neuroscience and/or vascular biology.
• You have extensive experience in imaging methodologies including whole mount immunofluorescence stainings and you have good knowledge of analysis methods for imaging datasets.
• Experience with dural/leptomeningeal biology and anatomy will be beneficial.
• You are passionate about answering fundamental questions in neurovascular biology with high translational impact.

Additional Information

The preferred start date of the internship is July 2026 or upon availability. Please clearly indicate your preferred starting date on your cover letter.

Application Process

Applications need to include a CV and a cover letter, as well as a letter from your current or former academic supervisor supporting your application to the RiSE Program.
Please note that due to regulations non-EU/EFTA citizens have to be enrolled at a university and provide a certificate from the university stating that an industry internship is mandatory as part of the university training.

Curious, motivated, and ready to learn? Apply now for our RiSE Internship.

Wer wir sind

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.